The Florida Keys are divided into five regions. Your trip begins at Key Largo, just south of Homestead, Fla., then runs through Islamorada, Marathon, Big Pine and the Lower Keys before coming to an end in Key West. Each region offers its own unique atmosphere and attractions.Key Largo, the longest of the islands, is home to John Pennekamp Coral Reef State Park, the first underwater preserve in the country and part of the Florida Keys National Marine Sanctuary. The park shelters 55 varieties of delicate corals and more than 600 species of fish.
Islamorada bills itself as the Sport-Fishing Capital of the World for the astounding diversity of angling opportunities and fighting fish including everything from sailfish, marlin and grouper in the open waters and tarpon and bonefish in the shallow coastal areas. And it's also the location of HGTV Dream Home 2008.
Marathon is considered the heart of the Florida Keys and also contains one of the area's most familiar landmarks, the Seven Mile Bridge. The area is also home to Crane Point, an important historical and archaeological site that contains evidence of pre-Columbian and prehistoric Bahamian artifacts.
Big Pine Key and the Lower Keys are known for the amazing shallow-water diving opportunities of the Looe Key Reef. The Bahia Honda State Park features beaches that regularly rank in the top 10 in the United States. Big Pine Key also features a national refuge for miniature Key deer, tropical forest and even a few alligators.
Finally your journey ends with the sunset at Key West, where you're closer to Cuba than to Miami. The tiny 2 by 4-mile island is noted for its artistic community, galleries, popularity among writers and of course the legendary dining and entertainment opportunities along Duval Street.
Visit Ernest Hemingway's former home where some 60 cats now prowl the grounds, many of them descendants of the author's famed six-toed tabby. Other wonders include the Mel Fisher Maritime Museum, displaying more than $400 million in gold and silver from the Nuestra Señora de Atocha, a 17th-century Spanish galleon that sank 45 miles off the coast.